Joy of Science Channel: Extreme Chemistry Series
“Boost and Lose Your Memory With Chemistry” A short presentation followed by Q&A with speaker Dr. Todd Sacktor, SUNY Downstate Medical Center.
What is your earliest memory? What about the happiest? Most painful? What if you could selectively enhance or remove certain memories, even long-term? The day may not be far off. Neuroscientist Todd Sacktor has discovered a way of selectively eliminating certain long-term memories in rats by turning an enzyme, PKMzeta, on and off. Then in 2011 he showed how increasing PKMzeta activity enhances long-term memories. Curious to learn more? Jog your memory and join us with speaker Todd Sacktor, at SUNY Downstate Medical Center, to learn about the future of chemistry and memory! Just don’t forget to register.
What You Will Learn
- The biochemical mechanism of long-term memory storage.
- How this enzymatic mechanism of memory storage leads to agents to erase and enhance long-term memories.
- Psychiatric and neurological disorders that may benefit from these manipulations.
- And much more…
Date: Thursday, November 3, 2011
Time: 2:00-3:00 pm ET
Meet Your Experts
Todd C. Sacktor completed an A.B. at Harvard College, M.D. at the Albert Einstein College of Medicine, and neurology residency at Columbia University. There he began studying the role of the enzyme protein kinase C (PKC) in the short-term memory of Aplysia, in the laboratory of Dr. James H. Schwartz, at Columbia’s Center for Neurobiology and Behavior, directed by Dr. Eric R. Kandel. In 1990, Sacktor established his own laboratory at the SUNY Downstate Medical Center, where he discovered a brain-specific isoform of protein kinase C, PKMzeta. In 2006, Sacktor and his colleagues uncovered PKMzeta’s impact in maintaining the brain’s long-term memory trace by showing, for the first time, that a long-term memory could be effectively erased by inhibiting a single molecule. In 2011, research showed that increasing PKMzeta activity in the brain enhances even old long-term memories. In 2006, the editors of Science highlighted Sacktor’s work on PKMzeta and memory as one of the top ten “Breakthroughs of the Year.” In 2009, his contributions were featured on the front page of The New York Times.
Darren Griffin, PhD is Professor of Genetics at the University of Kent, UK. Previously he was Professor of Genetics at Brunel University. In 2002, he was admitted as a fellow of the Society of Biology and in 2008 he was awarded both a fellowship of the Royal College of Pathologists and Doctor of Science from the University of Manchester. He was awarded the Institutional Teaching Prize for his work in supervising graduate students and was recently shortlisted for Research Project of the Year by the Times Higher Education supplement. Dr. Griffin completed his post-doctoral research in Cleveland, Ohio and at The University of Cambridge. He received his PhD at University College London in 1992, graduated from the University of Manchester in 1988.
The Fine Print
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